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Article

Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotype.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2007

Reimold M, Smolka M N, Schumann G, Zimmer A, Wrase J, Mann K, Hu X-Z, Goldman D, Reischl G, Solbach C, Machulla H-J, Bares R, Heinz A

Abstract excerpt

BACKGROUND: Homozygote carriers of two long (L) alleles of the serotonin transporter (5-HTT) regulatory region displayed in vitro a twofold increase in 5-HTT expression compared with carriers of one or two short (S) alleles. However, in vivo imaging studies yielded contradictory results. Recently, an A > G exchange leading to differential transcriptional activation of 5-HTT mRNA in lymphobalstoid cell lines was...

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Source

Identifiers

PMID: 17225932
DOI: 10.1007/s00702-006-0609-0

Genes

HTT

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Midbrain serotonin transporter binding potential measured with [11C]DASB is affected by serotonin transporter genotype.PMID 17225932Read ↗

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