Article
Genetic variation in HTR2A influences serotonin transporter binding potential as measured using PET and [11C]DASB.
The international journal of neuropsychopharmacology - 1 Jul 2010
Laje Gonzalo, Cannon Dara M, Allen Andrew S, Klaver Jackie M, Peck Summer A, Liu Xinmin, Manji Husseini K, Drevets Wayne C, McMahon Francis J
Abstract excerpt
In a previous study we showed that genetic variation in HTR2A, which encodes the serotonin 2A receptor, influenced outcome of citalopram treatment in patients with major depressive disorder. Since chronic administration of citalopram, which selectively and potently inhibits the serotonin transpor...
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