Article
Effect of a triallelic functional polymorphism of the serotonin-transporter-linked promoter region on expression of serotonin transporter in the human brain.
The American journal of psychiatry - 1 Jan 2006
Parsey Ramin V, Hastings Ramin S, Oquendo Maria A, Hu Xianzhang, Goldman David, Huang Yung-yu, Simpson Norman, Arcement Julie, Huang Yiyun, Ogden R Todd, Van Heertum Ronald L, Arango Victoria, Mann J John
Abstract excerpt
OBJECTIVE: The authors examined effects of a triallelic functional polymorphism of the human serotonin-transporter-linked promoter region (5-HTTLPR) on in vivo expression of serotonin transporter in the brain in healthy volunteers and subjects with major depressive disorder. METHOD: Twenty-five medication-free subjects with DSM-IV major depressive disorder during a major depressive episode and 42 healthy...
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