Article
Hepatitis B virus genotype A rarely circulates as an HBe-minus mutant: possible contribution of a single nucleotide in the precore region.
Journal of virology - 1 Sept 1993
Li J S, Tong S P, Wen Y M, Vitvitski L, Zhang Q, Trépo C
Abstract excerpt
The emergence of HBe-minus hepatitis B virus (HBV) mutants, usually through a UAG nonsense mutation at codon 28 of the precore region, helps the virus to survive the anti-HBe immune response of the host. Host and viral factors that predispose to the emergence of such mutants are not well characte...
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