Article
eIF4E function in somatic cells modulates ageing in Caenorhabditis elegans.
Nature - 22 Feb 2007
Syntichaki Popi, Troulinaki Kostoula, Tavernarakis Nektarios
Abstract excerpt
Regulation of protein synthesis is critical for cell growth and maintenance. Ageing in many organisms, including humans, is accompanied by marked alterations in both general and specific protein synthesis. Whether these alterations are simply a corollary of the ageing process or have a causative role in senescent decline remains unclear. An array of protein factors facilitates the tight control of messenger RNA...
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