Article
Translation of a small subset of Caenorhabditis elegans mRNAs is dependent on a specific eukaryotic translation initiation factor 4E isoform.
Molecular and cellular biology - 1 Jan 2005
Dinkova Tzvetanka D, Keiper Brett D, Korneeva Nadejda L, Aamodt Eric J, Rhoads Robert E
Abstract excerpt
The mRNA cap-binding protein eukaryotic translation initiation factor 4E (eIF4E) participates in protein synthesis initiation, translational repression of specific mRNAs, and nucleocytoplasmic shuttling. Multiple isoforms of eIF4E are expressed in a variety of organisms, but their specific roles are poorly understood. We investigated one Caenorhabditis elegans isoform, IFE-4, which has homologues in plants and...
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