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Article

Identification of cross-neutralization determinants by GAP analysis: a mutational behavior approach.

Current HIV research - 1 Jan 2007

Li Fusheng, Gilbert Peter B, Self Steve G

Abstract excerpt

Antigenic variation, which is the result of amino acid substitution and genetic evolution, poses a major challenge in the development of vaccines against pathogens with unstable genomes, such as HIV-1 and Influenza. Thus, it is highly important to characterize the relationship of genetic evolution, antigenic variation and positional mutation (GAP) from the perspective of vaccine development. For this purpose, we...

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Share to Antigenic Variation
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hemagglutinin Glycoproteins, Influenza Virus

Share to Influenza A Virus, H3N2 Subtype

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Source

Identifiers

PMID: 17266560
DOI: 10.2174/157016207779316305

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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