Article

Predicting viral sensitivity to antibodies using genetic sequences and antibody similarities

2025-08-11

Abstract excerpt

For genetically variable pathogens such as human immunodeficiency virus (HIV)-1, individual viral isolates can differ dramatically in their sensitivity to antibodies. The ability to predict which viruses will be sensitive and which will be resistant to a specific antibody could aid in the design of antibody therapies and help illuminate resistance evolution. Due to the enormous number of possible combinations, it...

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Literature Corpus work: 825872d8-384e-545c-8775-56e43e1e408d
DOI: 10.1101/2025.08.08.669352

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