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Article

Deciphering the rule of antigen-antibody amino acid interaction.

Frontiers in immunology - 1 Jan 2023

Jiang Min, Fang Changyin, Ma Yongping

Abstract excerpt

Purpose: Antigenic drift is the biggest challenge for mutagenic RNA virus vaccine development. The primary purpose is to determine the IEMM (immune escape mutation map) of 20 amino acids' replacement to reveal the rule of the viral immune escape. Methods: To determine the relationship between epitope mutation and immune escape, we use universal protein tags as a linear epitope model. To describe and draw amino...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38111576
DOI: 10.3389/fimmu.2023.1269916
PMCID: PMC10725943

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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