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Article

Where FoxP3-dependent regulatory T cells impinge on the development of inflammatory arthritis.

Arthritis and rheumatism - 1 Feb 2007

Nguyen Linh T, Jacobs Jonathan, Mathis Diane, Benoist Christophe

Abstract excerpt

OBJECTIVE: Regulatory T cells play a suppressive role in many autoimmune diseases and can potentially affect various steps in the progression of disease. The purpose of this study was to analyze the role of Treg cells in the control of arthritis development. METHODS: Using crosses and cell transfers, we tested the effect of the scurfy loss-of-function mutation of the Foxp3 gene in the K/BxN mouse model. In this...

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Identifiers

PMID: 17265486
DOI: 10.1002/art.22272

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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