Article
Persistence of K103N-containing HIV-1 variants after single-dose nevirapine for prevention of HIV-1 mother-to-child transmission.
The Journal of infectious diseases - 1 Mar 2007
Flys Tamara S, Donnell Deborah, Mwatha Anthony, Nakabiito Clemensia, Musoke Philippa, Mmiro Francis, Jackson J Brooks, Guay Laura A, Eshleman Susan H
Abstract excerpt
K103N-containing human immunodeficiency virus (HIV)-1 variants are selected in some women who receive single-dose (SD) nevirapine (NVP) for prevention of HIV-1 mother-infant transmission. We examined the persistence of K103N in women who received SD NVP prophylaxis. K103N was detected using the LigAmp assay (assay cutoff, 0.5% K103N). K103N was detected at 6-8 weeks in 60 (41.7%) of 144 women. Fading (lack of...
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