Article
HIV type 1 variants with nevirapine resistance mutations are rarely detected in antiretroviral drug-naive African women with subtypes A, C, and D.
AIDS research and human retroviruses - 1 Jun 2007
Church Jessica D, Hudelson Sarah E, Guay Laura A, Chen Shu, Hoover Donald R, Parkin Neil, Fiscus Susan A, Mmiro Francis, Musoke Philippa, Kumwenda Newton, Jackson J Brooks, Taha Taha E, Eshleman Susan H
Abstract excerpt
K103N is frequently detected in HIV-infected women after single dose (SD) nevirapine (NVP). K103N-containing variants were detected more frequently by the ViroSeq HIV-1 Genotyping System in women with subtype C (69.2%) than subtypes A (19.4%, p < 0.0001) or D (36.1%, p < 0.0001). K103N-containing variants were also detected more frequently and at higher levels in women with subtype C by the LigAmp assay. In this...
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