Article
Sensitivity of the ViroSeq HIV-1 genotyping system for detection of the K103N resistance mutation in HIV-1 subtypes A, C, and D.
The Journal of molecular diagnostics : JMD - 1 Sept 2006
Church Jessica D, Jones Dana, Flys Tamara, Hoover Donald, Marlowe Natalia, Chen Shu, Shi Chanjuan, Eshleman James R, Guay Laura A, Jackson J Brooks, Kumwenda Newton, Taha Taha E, Eshleman Susan H
Abstract excerpt
The US Food and Drug Administration-cleared ViroSeq HIV-1 Genotyping System (ViroSeq) and other population sequencing-based human immunodeficiency virus type 1 (HIV-1) genotyping methods detect antiretroviral drug resistance mutations present in the major viral population of a test sample. These assays also detect some mutations in viral variants that are present as mixtures. We compared detection of the K103N...
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