Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses.

Hepatology (Baltimore, Md.) - 1 Jun 2014

Osburn William O, Snider Anna E, Wells Brittany L, Latanich Rachel, Bailey Justin R, Thomas David L, Cox Andrea L, Ray Stuart C

Abstract excerpt

UNLABELLED: The contribution of humoral immune responses to spontaneous control of hepatitis C virus (HCV) infection remains unclear. We assessed neutralizing antibody (nAb) responses during acute HCV infection to determine whether infection outcome is associated with the nAb response, specifically, its timing or breadth (neutralization of multiple genotype-matched variants). A representative genotype 1 HCV...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibodies, Neutralizing
Share to Cohort Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Hepacivirus

Share to Hepatitis C

Share to Hepatitis C Antibodies

Share to HLA-DQ Antigens

Share to Polymorphism, Single Nucleotide

Share to Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 24425349
DOI: 10.1002/hep.27013
PMCID: PMC4043926

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Clearance of hepatitis C infection is associated with the early appearance of broad neutralizing antibody responses.PMID 24425349Read ↗

Broad Anti-Hepatitis C Virus (HCV) Antibody Responses Are Associated with Improved Clinical Disease Parameters in Chronic HCV Infection.Semantic proximity Read ↗

Repeated exposure to heterologous hepatitis C viruses associates with enhanced neutralizing antibody breadth and potencySemantic proximity Read ↗

Hepatitis C virus continuously escapes from neutralizing antibody and T-cell responses during chronic infection in vivo.Semantic proximity Read ↗

A Diverse Panel of Hepatitis C Virus Glycoproteins for Use in Vaccine Research Reveals Extremes of Monoclonal Antibody Neutralization ResistanceSemantic proximity Read ↗

Defining Breadth of Hepatitis C Virus Neutralization.Semantic proximity Read ↗

B cell immunodominance in primary hepatitis C virus infection.Semantic proximity Read ↗

Hepatitis C Virus Genetic Variability, Human Immune Response, and Genome Polymorphisms: Which Is the Interplay?Semantic proximity Read ↗

Characterization of linear epitope specificity of antibodies potentially contributing to spontaneous clearance of hepatitis C virus.Semantic proximity Read ↗

Antigenicity of key hepatitis C virus E1E2 glycoprotein neutralizing sites is genotype independent.Semantic proximity Read ↗

Human serum facilitates hepatitis C virus infection, and neutralizing responses inversely correlate with viral replication kinetics at the acute phase of hepatitis C virus infection.Semantic proximity Read ↗

Hepatitis C patient-derived glycoproteins exhibit marked differences in susceptibility to serum neutralizing antibodies: genetic subtype defines antigenic but not neutralization serotype.Semantic proximity Read ↗

A Hepatitis C Virus Envelope Polymorphism Confers Resistance to Neutralization by Polyclonal Sera and Broadly Neutralizing Monoclonal AntibodiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.