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Article

B cell immunodominance in primary hepatitis C virus infection.

Journal of hepatology - 1 Apr 2020

Brasher Nicholas A, Eltahla Auda A, Underwood Alexander, Boo Irene, Rizzetto Simone, Walker Melanie R, Rodrigo Chaturaka, Luciani Fabio, Maher Lisa, Drummer Heidi E, Tedla Nicodemus, Lloyd Andrew R, Bull Rowena A

Abstract excerpt

BACKGROUND & AIMS: Neutralising antibodies (NAbs) play a key role in clearance of HCV. NAbs have been isolated and mapped to several domains on the HCV envelope proteins. However, the immunodominance of these epitopes in HCV infection remains unknown, hindering efforts to elicit optimal epitope-specific responses. Furthermore, it remains unclear which epitope-specific responses are associated with broad NAb...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31785346
DOI: 10.1016/j.jhep.2019.11.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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