Article
Association of a single nucleotide polymorphism in TNIP1 with type-1 autoimmune hepatitis in the Japanese population.
Journal of human genetics - 1 Jun 2018
Oka Shomi, Higuchi Takashi, Furukawa Hiroshi, Nakamura Minoru, Komori Atsumasa, Abiru Seigo, Nagaoka Shinya, Hashimoto Satoru, Naganuma Atsushi, Naeshiro Noriaki, Yoshizawa Kaname, Shimada Masaaki, Nishimura Hideo, Tomizawa Minoru, Kikuchi Masahiro, Makita Fujio, Yamashita Haruhiro, Ario Keisuke, Yatsuhashi Hiroshi, Tohma Shigeto, Kawasaki Aya, Tsuchiya Naoyuki, Migita Kiyoshi
Abstract excerpt
Several studies reported that autoimmune diseases share a number of susceptibility genes. Of these genes, a SNP rs7708392 in TNIP1 was reported to be associated with systemic lupus erythematosus (SLE). Autoimmune hepatitis (AIH), a rare chronic progressive liver disease, shares some clinical features with SLE. Therefore, we investigated whether the SNP is associated with Japanese AIH. An association study of...
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