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Article

Genetic risk factors for autoimmune hepatitis: implications for phenotypic heterogeneity and biomarkers for drug response.

Human genomics - 28 Jan 2021

Higuchi Takashi, Oka Shomi, Furukawa Hiroshi, Tohma Shigeto, Yatsuhashi Hiroshi, Migita Kiyoshi

Abstract excerpt

Autoimmune hepatitis (AIH) is a rare chronic progressive liver disease with autoimmune features. It mainly affects middle-aged women. AIH is occasionally complicated with liver cirrhosis that worsens the prognosis. Genetic and environmental factors are involved in the pathogenesis of AIH. Genetic studies of other diseases have been revealing of pathogenesis and drug efficacy. In this review, we summarize the...

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Identifiers

PMID: 33509297
DOI: 10.1186/s40246-020-00301-4
PMCID: PMC7841991

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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