Article
Genetic background of autoimmune hepatitis in Japan.
Journal of gastroenterology - 1 Jan 2011
Yoshizawa Kaname, Umemura Takeji, Ota Masao
Abstract excerpt
Autoimmune hepatitis (AIH) is an organ-specific autoimmune disease characterized by chronic inflammation of the liver. Several studies from ethnically different countries have clarified that the genetic predisposition to type 1 AIH is linked mainly to human leukocyte antigen (HLA)-class II genes. Recently, molecular analysis using polymerase chain reaction (PCR)-based DNA typing has revealed that susceptibility...
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