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Article

Apolipoprotein E and cognitive performance: a meta-analysis.

Psychology and aging - 1 Dec 2004

Small Brent J, Rosnick Christopher B, Fratiglioni Laura, Bäckman Lars

Abstract excerpt

The epsilon4 allele of the apolipoprotein E (APOE) gene is a known risk factor for Alzheimer's disease and may also affect cognitive performance in normal aging. Evidence of the presence and magnitude of epsilon4-related cognitive deficits was examined with a meta-analysis of the available litera...

Topics

Adult
Aged
Aged, 80 and over
Aging
Alleles
Alzheimer Disease
Apolipoprotein E4
Apolipoproteins E
Cognition
Female
Genetic Carrier Screening
Genotype
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Middle Aged

Neuropsychological Tests

Reaction Time

Source

Identifiers

PMID: 15584785
DOI: 10.1037/0882-7974.19.4.592

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-15584785-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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