Apolipoprotein epsilon4 and neuropsychological performance in Alzheimer's disease and vascular dementia.

doi:10.1016/j.neulet.2010.07.063

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Article

Apolipoprotein epsilon4 and neuropsychological performance in Alzheimer's disease and vascular dementia.

Neuroscience letters - 8 Oct 2010

McGuinness Bernadette, Carson Robyn, Barrett Suzanne Lucia, Craig David, Passmore Anthony Peter

Abstract excerpt

The apolipoprotein (APOE) epsilon4 allele is a genetic risk factor for the development of Alzheimer's disease (AD). It has also been associated with vascular dementia (VaD) in some but not all studies. Previous studies have examined the role of APOE in predicting performance on cognitive tests in both demented and non-demented populations. In cognitively intact individuals, statistically significant group...

Topics

Aged
Aged, 80 and over
Alleles
Alzheimer Disease
Analysis of Variance
Apolipoprotein E4
Attention
Cognition
Dementia, Vascular
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype
Humans
Male
Memory
Neuropsychological Tests
Reaction Time

Source

Open in PubMed

Identifiers

PMID: 20678545
DOI: 10.1016/j.neulet.2010.07.063

Genes

APOE

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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