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Article

Is APOE--epsilon4 a risk factor for cognitive impairment in normal aging?

Neurology - 13 Jun 2000

Small B J, Graves A B, McEvoy C L, Crawford F C, Mullan M, Mortimer J A

Abstract excerpt

OBJECTIVES: To examine the relationship between APOE genotype and cognitive functioning in normal aging, and to determine whether this relationship was moderated by age or the presence of a number of disease conditions, including cardiovascular disease and diabetes. METHODS: The sample was drawn from the Charlotte County Healthy Aging Study, a community-based, cross-sectional study of randomly selected older...

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Source

Identifiers

PMID: 10851367
DOI: 10.1212/wnl.54.11.2082

Genes

APOE

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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