Article
Acecainide pharmacokinetics in normal subjects of known acetylator phenotype.
Biopharmaceutics & drug disposition - 1 Nov 1991
Coyle J D, Boudoulas H, Lima J J
Abstract excerpt
The purpose of this study was to determine the pharmacokinetics of acecainide (formerly N-acetylprocainamide) in six normal subjects of known acetylator phenotype. Three subjects were fast acetylators and three slow acetylators by sulfapyridine phenotyping criteria. Each subject received a 20-min...
Topics
- Acecainide
- Acetylation
- Adult
- Humans
- Male
- Phenotype
- Procainamide
