Article
Translation efficiencies of the 5'-untranslated region of genotypes 1a and 3a in hepatitis C infected patients.
Journal of medical virology - 1 Mar 2007
Motazakker M, Preikschat P, Elliott J, Smith C A, Mills P R, Oien K, Spence E, Elliott R M, McCruden E A B
Abstract excerpt
Differences between the translation efficiencies mediated by the 5'-untranslated regions (5'-UTR) of genotypes (gt) 1 and 3 of hepatitis C virus (HCV) have been reported but it is unknown if such differences are biologically significant. The 5'-UTR was sequenced from paired serum and liver samples from 26 patients with chronic HCV hepatitis (11 gt 1a, 15 gt 3a). To determine whether there is a consistent...
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