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Article

Internal initiation of translation efficiency in different hepatitis C genotypes isolated from interferon treated patients.

Archives of virology - 1 Jan 1999

Sáiz J C, López de Quinto S, Ibarrola N, López-Labrador F X, Sánchez-Tapias J M, Rodés J, Martínez-Salas E

Abstract excerpt

Initiation of translation of hepatitis C viral RNA occurs internally and it is mediated by a segment of about 330 nucleotides termed Internal Ribosome Entry Site (IRES) located in the 5' end region. While being the most conserved part of the genome, this region also accumulates nucleotide substitutions which are often covariant. In this study we have examined the activity and sequence variation of IRES elements...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 10470249
DOI: 10.1007/s007050050499

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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