Article
Dietary intake of folate and co-factors in folate metabolism, MTHFR polymorphisms, and reduced rectal cancer.
Cancer causes & control : CCC - 1 Mar 2007
Murtaugh Maureen A, Curtin Karen, Sweeney Carol, Wolff Roger K, Holubkov Richard, Caan Bette J, Slattery Martha L
Abstract excerpt
Little is known about the contribution of polymorphisms in the methylenetetrahydrofolate reductase gene (MTHFR) and the folate metabolism pathway in rectal cancer alone. Data were from participants in a case-control study conducted in Northern California and Utah (751 cases and 979 controls). We examined independent associations and interactions of folate, B vitamins, methionine, alcohol, and MTHFR polymorphisms...
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