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Article

Polymorphisms of folate metabolic genes and susceptibility to bladder cancer: a case-control study.

Carcinogenesis - 1 Sept 2004

Lin Jie, Spitz Margaret R, Wang Yunfei, Schabath Matthew B, Gorlov Ivan P, Hernandez Ladia M, Pillow Patricia C, Grossman H Barton, Wu Xifeng

Abstract excerpt

Epidemiological studies have shown an association between low folate intake and an increased cancer risk. Major genes involved in folate metabolism include methylene-tetrahydrofolate reductase (MTHFR) and methionine synthase (MS). We investigated joint effects of polymorphisms of the MTHFR (677 C-->T, 1298A-->C) and MS genes (2756 A-->G), dietary folate intake and cigarette smoking on the risk of bladder cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15117811
DOI: 10.1093/carcin/bgh175

Genes

MTHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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