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Article

A methylenetetrahydrofolate reductase polymorphism and the risk of colorectal cancer.

Cancer research - 1 Nov 1996

Chen J, Giovannucci E, Kelsey K, Rimm E B, Stampfer M J, Colditz G A, Spiegelman D, Willett W C, Hunter D J

Abstract excerpt

We examined the relationship of a common polymorphism (667C-->T) of the methylenetetrahydrofolate reductase (MTHFR) gene with the risk of colorectal cancer in a case-control study conducted in the Health Professionals Follow-up Study. MTHFR genotypes were ascertained from blood samples among 144 men previously diagnosed with colorectal cancer and 627 controls. The adjusted odds ratio (OR) for the MTHFR variant...

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Source

Identifiers

PMID: 8895734

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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