Article
A basic region neighboring the lysine-rich C-terminus of protein SRP19 is required for binding to signal recognition particle RNA.
Biochemistry and cell biology = Biochimie et biologie cellulaire - 1 Sept 1991
Zwieb C
Abstract excerpt
To identify some of the determinants in the 19-kilodalton protein of signal recognition particle (SRP19) for binding to signal recognition particle RNA, two mutant derivatives of the SRP19 were constructed, lacking 14 and 24 C-terminal amino acids. Polypeptides were transcribed and translated in vitro and tested for their ability to bind to signal recognition particle RNA by retention of protein-RNA complexes on...
Topics
- Amino Acid Sequence
- Animals
- Base Sequence
- Binding Sites
- Lysine
- Molecular Sequence Data
- Mutation
- Protein Biosynthesis
- RNA
- RNA, Messenger
- Rats
- Ribonucleoproteins