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Article

Assembly of the human signal recognition particle (SRP): overlap of regions required for binding of protein SRP54 and assembly control.

RNA (New York, N.Y.) - 1 Oct 2001

Yin J, Yang C H, Zwieb C

Abstract excerpt

Assembly of the human signal recognition particle (SRP) entails the incorporation of protein SRP54, mediated by a protein SRP1 9-induced conformational change in SRP RNA. To localize the region that controls this crucial step in the assembly of human SRP RNA, four chimeras, Ch-1 to Ch-4, composed of portions of human and Methanococcus jannashii SRP RNAs, were generated by PCR site-directed mutagenesis from a...

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Source

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Identifiers

PMID: 11680843
PMCID: PMC1370182

Genes

SRP19
SRP54

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Assembly of the human signal recognition particle (SRP): overlap of regions required for binding of protein SRP54 and assembly control.PMID 11680843Read ↗

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