Article
Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity.
Annals of the New York Academy of Sciences - 1 Dec 2007
Lipsky Robert H, Marini Ann M
Abstract excerpt
Neurotrophins are critical to the development and maintenance of the mammalian central nervous system. Among them is brain-derived neurotrophic factor (BDNF), whose synthesis and release is targeted by activation of glutamate receptors. Perturbation of this process probably underlies neurodegenerative and psychiatric disorders. A naturally occurring variation in humans, in the form of a common single-nucleotide...
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