Article
Nucleotide sequence diversity in non-coding regions of ALDH2 as revealed by restriction enzyme and SSCP analysis.
Human genetics - 1 Feb 1999
Peterson R J, Goldman D, Long J C
Abstract excerpt
The simultaneous analysis of closely linked nucleotide substitutions has recently become possible. However, it is not known whether the construction of molecular haplotypes will be a generally useful strategy for nuclear genes. Furthermore, whereas mobility-shift methods are widely used for the discovery of nucleotide substitutions, the yield of these methods has rarely been evaluated. This paper investigates...
Read the complete abstract on PubMedTopics
- Aldehyde Dehydrogenase
- Aldehyde Dehydrogenase, Mitochondrial
- Alleles
- DNA Restriction Enzymes
- Gene Frequency
- Genetic Variation