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Article

Ascertainment bias in studies of human genome-wide polymorphism.

Genome research - 1 Nov 2005

Clark Andrew G, Hubisz Melissa J, Bustamante Carlos D, Williamson Scott H, Nielsen Rasmus

Abstract excerpt

Large-scale SNP genotyping studies rely on an initial assessment of nucleotide variation to identify sites in the DNA sequence that harbor variation among individuals. This "SNP discovery" sample may be quite variable in size and composition, and it has been well established that properties of the SNPs that are found are influenced by the discovery sampling effort. The International HapMap project relied on...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16251459
DOI: 10.1101/gr.4107905
PMCID: PMC1310637

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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