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Article

Genome-Wide Natural Selection Signatures Are Linked to Genetic Risk of Modern Phenotypes in the Japanese Population.

Molecular biology and evolution - 1 May 2020

Yasumizu Yoshiaki, Sakaue Saori, Konuma Takahiro, Suzuki Ken, Matsuda Koichi, Murakami Yoshinori, Kubo Michiaki, Palamara Pier Francesco, Kamatani Yoichiro, Okada Yukinori

Abstract excerpt

Elucidation of natural selection signatures and relationships with phenotype spectra is important to understand adaptive evolution of modern humans. Here, we conducted a genome-wide scan of selection signatures of the Japanese population by estimating locus-specific time to the most recent common ancestor using the ascertained sequentially Markovian coalescent (ASMC), from the biobank-based large-scale...

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Identifiers

PMID: 31957793
DOI: 10.1093/molbev/msaa005
PMCID: PMC7182208

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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