Article
Ex vivo interleukin 1 receptor antagonist production on lipopolysaccharide stimulation is associated with rheumatoid arthritis and with joint damage.
Annals of the rheumatic diseases - 1 Aug 2007
de Vries-Bouwstra J K, Goekoop-Ruiterman Y P M, Wesoly J, Hulsmans H J, de Craen A J M, Breedveld F C, Dijkmans B A C, Allaart C F, Huizinga T W J
Abstract excerpt
OBJECTIVES: (1) To assess innate ex vivo production of interleukin 1beta (IL1beta) and interleukin 1 receptor antagonist (IL1Ra) in patients with recent-onset rheumatoid arthritis (RA) as compared with healthy controls; (2) to assess the association of ex vivo IL1beta and IL1Ra production with progression of joint damage in RA; (3) to determine whether differences in ex vivo IL1beta production are explained by...
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