Article
A broad analysis of IL1 polymorphism and rheumatoid arthritis.
Arthritis and rheumatism - 1 Jul 2008
Johnsen Alyssa K, Plenge Robert M, Butty Vincent, Campbell Christopher, Dieguez-Gonzalez Rebeca, Gomez-Reino Juan J, Shadick Nancy, Weinblatt Michael, Gonzalez Antonio, Gregersen Peter K, Benoist Christophe, Mathis Diane
Abstract excerpt
OBJECTIVE: It has been suggested that polymorphisms in IL1 are correlated with severe and/or erosive rheumatoid arthritis (RA), but the implicated alleles have differed among studies. The aim of this study was to perform a broad and well-powered search for association between allelic polymorphism in IL1A and IL1B and the susceptibility to or severity of RA. METHODS: Key coding and regulatory regions in IL1A and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
