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Article

Functional consequences of DECTIN-1 early stop codon polymorphism Y238X in rheumatoid arthritis.

Arthritis research & therapy - 1 Jan 2010

Plantinga Theo S, Fransen Jaap, Takahashi Nozomi, Stienstra Rinke, van Riel Piet L, van den Berg Wim B, Netea Mihai G, Joosten Leo Ab

Abstract excerpt

INTRODUCTION: Dectin-1, a pattern recognition receptor expressed by the innate immune system, is known to be a major receptor inducing Th17-type adaptive immune responses that have been demonstrated to mediate autoimmunity. In this study, dectin-1 mRNA and protein expression, as well as the recently characterized DECTIN-1 Y238X early stop codon polymorphism, were studied in relation to rheumatoid arthritis (RA)...

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Identifiers

PMID: 20158887
DOI: 10.1186/ar2933
PMCID: PMC2875660

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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