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Article

Amplification of lac cannot account for adaptive mutation to Lac+ in Escherichia coli.

Journal of bacteriology - 1 Mar 2007

Stumpf Jeffrey D, Poteete Anthony R, Foster Patricia L

Abstract excerpt

When the Lac- strain of Escherichia coli, FC40, is incubated with lactose as its sole carbon and energy source, Lac+ revertants arise at a constant rate, a phenomenon known as adaptive mutation. Two alternative models for adaptive mutation have been proposed: (i) recombination-dependent mutation, which specifies that recombination occurring in nongrowing cells stimulates error-prone DNA synthesis, and (ii)...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 17209030
DOI: 10.1128/JB.01706-06
PMCID: PMC1899370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Amplification of lac cannot account for adaptive mutation to Lac+ in Escherichia coli.PMID 17209030Read ↗

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Mechanisms of mutation in nondividing cells. Insights from the study of adaptive mutation in Escherichia coli.Semantic proximity Read ↗

Amplification-mutagenesis: evidence that "directed" adaptive mutation and general hypermutability result from growth with a selected gene amplification.Semantic proximity Read ↗

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