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Article

Mechanisms of directed mutation.

Genetics - 1 Aug 1992

Foster P L, Cairns J

Abstract excerpt

Spontaneous mutants arise among nondividing populations of Escherichia coli in apparent response to selective conditions. In this report we investigate several hypotheses to account for the role of selection in the production of these "directed" or "adaptive" mutations. We found that the Lac+ phenotypes of some mutants that arise late after lactose selection are due to suppressor mutations that are unlinked to...

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Identifiers

PMID: 1516815
DOI: 10.1093/genetics/131.4.783
PMCID: PMC1205091

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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