Mechanisms of directed mutation.

doi:10.1093/genetics/131.4.783

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Article

Mechanisms of directed mutation.

Genetics - 1 Aug 1992

Foster P L, Cairns J

Abstract excerpt

Spontaneous mutants arise among nondividing populations of Escherichia coli in apparent response to selective conditions. In this report we investigate several hypotheses to account for the role of selection in the production of these "directed" or "adaptive" mutations. We found that the Lac+ phe...

Topics

DNA Repair
DNA, Bacterial
Escherichia coli
Lactose
Models, Genetic
Mutation
Phenotype
Selection, Genetic
Transcription, Genetic

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