Article
Nonadaptive mutations occur on the F' episome during adaptive mutation conditions in Escherichia coli.
Journal of bacteriology - 1 Mar 1997
Foster P L
Abstract excerpt
One of the most studied examples of adaptive mutation is a strain of Escherichia coli, FC40, that cannot utilize lactose (Lac-) but that readily reverts to lactose utilization (Lac+) when lactose is its sole carbon source. Adaptive reversion to Lac+ occurs at a high rate when the Lac- allele is on an F' episome and conjugal functions are expressed. It was previously shown that nonselected mutations on the...
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