Article
Genetic association study of GABRA2 single nucleotide polymorphisms and electroencephalography in alcohol dependence.
Neuroscience letters - 18 Aug 2011
Lydall G J, Saini J, Ruparelia K, Montagnese S, McQuillin A, Guerrini I, Rao H, Reynolds G, Ball D, Smith I, Thomson A D, Morgan M Y, Gurling H M D
Abstract excerpt
The gamma aminobutyric acid (GABA) system has been implicated in the susceptibility to develop alcohol dependence and in determining electroencephalogram (EEG) beta activity. The role of the GABA receptor alpha-2 gene (GABRA2) in human alcohol dependence was determined in a genetic and electrophysiological study. The study population comprised 586 white UK individuals with alcohol dependence but a very low...
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