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Article

Contribution of genetic and environmental factors in the pathogenesis of Crohn's disease in a large family with multiple cases.

Inflammatory bowel diseases - 1 May 2007

Joossens Marie, Simoens Marc, Vermeire Séverine, Bossuyt Xavier, Geboes Karel, Rutgeerts Paul

Abstract excerpt

BACKGROUND: A large family of Moroccan immigrants was investigated. In this family the father developed Crohn's disease (CD) after moving from Morocco to Belgium and successively 4 of his 8 children subsequently developed CD. There was no previous history of familial CD. METHODS: The family was interviewed at their home and an elaborated questionnaire was completed. The food and sanitation characteristics of the...

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Source

Identifiers

PMID: 17206668
DOI: 10.1002/ibd.20086

Genes

CARD8
DLG5
NOD1
TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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