Article
Association of deficiency for mannan-binding lectin with anti-mannan antibodies in Crohn's disease: a family study.
Inflammatory bowel diseases - 1 Sept 2007
Seibold Frank, Boldt Angelica B W, Seibold-Schmid Beatrice, Schoepfer Alain M, Flogerzi Beatrice, Müller Stefan, Kun Jürgen F J
Abstract excerpt
BACKGROUND: Antibodies against mannan, a component of the yeast Saccharomyces cerevisiae cell wall, are more frequently found in Crohn's disease (CD) patients with low levels of mannan-binding lectin (MBL). MBL concentration depends on genetic polymorphisms. The aim of this study was to evaluate whether low MBL is related to ASCA production in healthy family members of CD patients. METHODS: ASCA and MBL...
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