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Article

Interaction between seroreactivity to microbial antigens and genetics in Crohn's disease: is there a role for defensins?

Tissue antigens - 1 Jun 2008

Lakatos P L, Altorjay I, Mándi Y, Lakatos L, Tumpek J, Kovacs A, Molnar T, Tulassay Z, Miheller P, Palatka K, Szamosi T, Fischer S, Papp J, Papp M

Abstract excerpt

Antibodies against different microbial epitopes are associated with disease phenotype, may be of diagnostic importance and may reflect a loss of tolerance in Crohn's disease (CD). Recently, an association was reported between the presence of these antibodies and mutations in pattern receptor gene...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18397186
DOI: 10.1111/j.1399-0039.2008.01049.x

Genes

DEFB1
DLG5
NOD1
NOD2
TLR4

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18397186-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Interaction between seroreactivity to microbial antigens and genetics in Crohn's disease: is there a role for defensins?PMID 18397186Read ↗

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