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Article

Increased intestinal permeability and NOD2 variants in familial and sporadic Crohn's disease.

Alimentary pharmacology & therapeutics - 15 May 2006

D'Incà R, Annese V, di Leo V, Latiano A, Quaino V, Abazia C, Vettorato M G, Sturniolo G C

Abstract excerpt

BACKGROUND: Abnormal barrier function may be genetically determined in Crohn's disease. AIM: To examine the role of abnormal intestinal permeability in genetic predisposition in multiplex vs. sporadic Crohn's disease families. METHODS: Intestinal permeability was measured in patients, relatives and partners by means of lactulose/mannitol test. Healthy subjects from the hospital staff served as controls. CARD15...

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Source

Identifiers

PMID: 16669960
DOI: 10.1111/j.1365-2036.2006.02916.x

Genes

NOD2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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