Article
Familial Crohn's disease: a study of 18 families.
Acta gastro-enterologica Belgica - 1 Jan 2000
Franchimont D, Belaiche J, Louis E, Simon S, GrandBastien B, Gower-Rousseau C, Fontaine F, Delforge M
Abstract excerpt
UNLABELLED: The high frequency of familial Crohn's disease (CD) suggests a genetic predisposition. The most recent data from epidemiology and molecular biology are consistent with a multifactorial, polygenic inheritance with a possible genetic heterogeneity. The aim of our study was, first to compare familial and sporadic CD on the basis of the type and location of the disease, and age at diagnosis, and second,...
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