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Article

Left-right dynein motor implicated in selective chromatid segregation in mouse cells.

Science (New York, N.Y.) - 5 Jan 2007

Armakolas Athanasios, Klar Amar J S

Abstract excerpt

During cell division, copies of mouse chromosome 7 are segregated selectively or randomly to daughter cells depending on the cell type. The mechanism for differential segregation is unknown. Because mouse left-right dynein (LRD) gene mutations result in randomization of visceral organs' laterality, we hypothesized that LRD may also function in selective chromatid segregation. Indeed, upon knock-down by RNA...

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Identifiers

PMID: 17204651
DOI: 10.1126/science.1129429

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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