Article
Mechanism of positioning the cell nucleus in vertebrate photoreceptors.
Proceedings of the National Academy of Sciences of the United States of America - 11 Sept 2007
Tsujikawa Motokazu, Omori Yoshihiro, Biyanwila Janisha, Malicki Jarema
Abstract excerpt
Organelles are frequently distributed in a nonrandom manner in a cell's cytoplasm. A particular distribution pattern often facilitates a specific function of a cell, whereas its aberrations can lead to cell death. We show that a mutation in the zebrafish mikre oko (mok) locus, which encodes dynactin 1 subunit of the dynactin complex, produces a severe displacement of the photoreceptor cell nucleus toward the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
