Article
Abnormalities in CD4+ T lymphocyte subsets in patients with common variable immunodeficiency.
Clinical immunology and immunopathology - 1 Oct 1991
Lebranchu Y, Thibault G, Degenne D, Bardos P
Abstract excerpt
In order to investigate whether deficient immunoglobulin production in common variable immunodeficiency (CVI) patients was related to defective T cells functions, phenotype and proliferative responses to mitogen of peripheral blood mononuclear cells (PBMC) were investigated in 9 patients with CVI. The results were compared to those of 12 age- and sex-matched normal controls. The numbers of CD3+ and CD8+ T cells...
Topics
- Adolescent
- Adult
- Antigens, CD
- CD4 Antigens
- CD4-Positive T-Lymphocytes
- Female
- Histocompatibility Antigens
- Humans
- Immunologic Deficiency Syndromes
- Integrin beta1
- Leukocyte Common Antigens
