Article
T-cell abnormalities in common variable immunodeficiency.
Pediatric research - 1 Jan 1993
Jaffe J S, Eisenstein E, Sneller M C, Strober W
Abstract excerpt
Common variable immunodeficiency (CVI) is a heterogeneous condition marked by a number of different immunologic defects. One group of patients, perhaps 60% of the CVI group as a whole, is characterized by T cells that produce reduced amounts of IL-2 (mRNA and protein product), IL-4, and IL-5 (mRN...
Topics
- Antigens, CD
- Antigens, Differentiation, T-Lymphocyte
- CD4-CD8 Ratio
- CD57 Antigens
- Humans
- Immunologic Deficiency Syndromes
- Lymphokines
- Phenotype
- RNA, Messenger
- T-Lymphocyte Subsets
- T-Lymphocytes