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Article

T-cell abnormalities in common variable immunodeficiency.

Pediatric research - 1 Jan 1993

Jaffe J S, Eisenstein E, Sneller M C, Strober W

Abstract excerpt

Common variable immunodeficiency (CVI) is a heterogeneous condition marked by a number of different immunologic defects. One group of patients, perhaps 60% of the CVI group as a whole, is characterized by T cells that produce reduced amounts of IL-2 (mRNA and protein product), IL-4, and IL-5 (mRNA) when stimulated with phytohemagglutinin. This defect does not extend to all lymphokines, however, because the cells...

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Source

Identifiers

PMID: 7679486
DOI: 10.1203/00006450-199305001-00128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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