Article
Defective interleukin-2 and interferon-gamma gene expression in response to antigen in a subgroup of patients with common variable immunodeficiency.
The Journal of allergy and clinical immunology - 1 Aug 1993
Fischer M B, Hauber I, Vogel E, Wolf H M, Mannhalter J W, Eibl M M
Abstract excerpt
Patients with common variable immunodeficiency (CVID) are heterogeneous in the clinical manifestations of the disease and in the underlying mechanisms leading to the immunodeficiency. The impairment of B-cell function can be due to an intrinsic defect of the B cells, a deficiency in the function...
Topics
- Adult
- Antigens
- B-Lymphocytes
- Common Variable Immunodeficiency
- Female
- Gene Expression
- Humans
- Immunoglobulins
- Interferon-gamma
- Interleukin-2
- Lymphocyte Activation
- Lymphocytes